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However, the regulation of FSP1 oxidoreductase activity or how its subcellular localization impacts its involvement in various physiological and pathological processes, remains to be further elucidated [180, 181, 183, 186]

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It suggests acute injuries may respond faster chronic injuries may require longer timelines rehabilitation quality likely matters heavily mechanical loading remains critical response variability is substantial placebo and natural healing cannot be excluded some users appear highly responsive others appear completely resistant